Research Associate (Limited Term)
University of Toronto Voir toutes les offres
- Toronto, ON
- 53.520-100.350 $ par an
- Permanent
- Temps-plein
Req ID: 47640
Faculty/Division: Faculty of Arts & Science
Department: Cell and Systems Biology
Campus: St. George (Downtown Toronto)
Existing Vacancy: YesDescription:DESCRIPTION:The Department of Cell & Systems Biology at the University of Toronto invites applications for a Research Associate (Limited Term) for a two (2) year term appointment. The anticipated start date is May 2026.The Research Associate will be intrinsically involved in research projects where they contribute, by way of their academic expertise, to the projects directed by the principal investigator Professor Jennifer Mitchell. The Research Associate will perform projects in the lab of Prof. Jennifer Mitchell in the Department of Cell and Systems Biology on the regulation of gene expression by mechanical signals occurring in the uterus and myometrial smooth muscle cells during pregnancy and labour. The Research Associate will perform and analyse stretch experiments, transcriptomes, conduct chromatin analysis and immunofluorescence, construct molecular reporters and tag endogenous genes. The Research Associate will construct fusions to signalling and transcriptional regulatory proteins to modulate their expression. In addition, the Research Associate will perform large-scale genetic screening and phenotypic assays such as CRISPR targeting screens and cell viability, gene expression and response to mechanical cues.The Research Associate will also be responsible for record keeping of the project research, tracking spending on reagents, ordering chemicals and reagents as required and contributing to the training of other lab members in techniques within the scope of their expertise.Applicants should apply online at the link below and include a covering letter, curriculum vitae and three reference names with their contact addresses and phone numbers. Any questions regarding this position should be directed to Prof. Jennifer Mitchell at .MINIMUM QUALIFICATIONS:Education:
- Candidate must have a Ph.D. in Molecular Genetics.
- Minimum of 3 years experience in cell culture and Yap signalling mechanisms.
- Expertise with myometrial smooth muscle stretch experiments and Degron Tagging of endogenous genes.
- Demonstrated academic and hands-on research experience in the impact of mechanical signaling on chromatin architecture and gene expression.
- Experience designing and executing complex experimental workflows, utilizing state of the art techniques including CRISPR/Cas9 genome editing, ATAC-seq and RNA-seq.
- Experience in carrying out research with a high degree of independence.
- Experience in laboratory operations and training others (graduate students) in overall lab to ensure efficient and productive research environment.
- Strong data analysis, record-keeping, and documentation skills.
- Ability to manage laboratory inventories, track reagent usage, and order supplies.
- Excellent analytical, problem-solving, and communications skills.
- Leadership and ability to direct and supervisor graduate students.
- Interpersonal skills to facilitate effective collaboration within the research group.
Employee Group: Research Associate
Personnel Subarea:Research Assoc
Appointment Type: Grant - Term
Schedule: Full-Time
Pay Scale Group & Hiring Zone: R01 -- Research Associates (Limited Term): $53,520 - $100,350
Job Category: Research Administration & TeachingDiversity StatementThe University of Toronto embraces Diversity and is building a culture of belonging that increases our capacity to effectively address and serve the interests of our global community. We strongly encourage applications from Indigenous Peoples, Black and racialized persons, women, persons with disabilities, and people of diverse sexual and gender identities. We value applicants who have demonstrated a commitment to equity, diversity and inclusion and recognize that diverse perspectives, experiences, and expertise are essential to strengthening our academic mission.As part of your application, you will be asked to complete a brief Diversity Survey. This survey is voluntary. Any information directly related to you is confidential and cannot be accessed by search committees or human resources staff. Results will be aggregated for institutional planning purposes. For more information, please see .Accessibility StatementThe University strives to be an equitable and inclusive community, and proactively seeks to increase diversity among its community members. Our values regarding equity and diversity are linked with our unwavering commitment to excellence in the pursuit of our academic mission.The University is committed to the principles of the Accessibility for Ontarians with Disabilities Act (AODA). As such, we strive to make our recruitment, assessment and selection processes as accessible as possible and provide accommodations as required for applicants with disabilities.If you require any accommodations at any point during the application and hiring process, please contact .