Senior Statistician II, Late Oncology

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  • Mississauga, ON
  • 109.149-143.258 $ par an
  • Contrat
  • Temps-plein
  • Il y a 3 jours
Are you ready to turn complex data into decisions that shape late-stage oncology development? Do you want your statistical judgment to be visible at the moments that matter for patients and the business?In this high-exposure role, you will guide the building, analysis and understanding of studies that inform pivotal decisions across our late oncology portfolio. You will partner with clinicians, clinical operations, regulatory and medical teams to bring statistical rigor to every stage of development—translating evidence into clear recommendations that accelerate delivery of life-changing medicines.You will operate at the intersection of science and decision-making: applying robust methods, stress-testing strategies through modelling and simulation, and communicating insights with clarity. You will be supported by experienced peers, yet trusted to own your work, improve how we operate, and help set the bar for quality across programs.Accountabilities:
  • Offer statistical support for planning experimental work and clinical studies. Build clear decision criteria and power plans to address the right questions with relevant evidence.
  • With mentorship from experienced statisticians, lead the development and analysis of complex studies. Support broader programs including preclinical investigations, regulatory submissions, commercialization activities, and interactions with senior governance bodies.
  • Simulation and modelling: Apply simulation and modelling to inform study build decisions, assess robustness and operating characteristics, and examine scenarios under pressure to minimize risks in development plans.
  • Analysis Planning and Execution: Develop Statistical Analysis Plans; produce analyses, graphics and tables for standard studies and reports across clinical, preclinical, medical affairs and publication needs with accuracy and timeliness.
  • Insightful Interpretation and Communication: Interpret, summarize and communicate findings from standard studies in a way that influences decisions and next steps, translating statistics into clear, actionable mentorship.
  • Methodology and Process Improvement: Contribute to improved methods and practical solutions that raise quality, efficiency and effectiveness; embed best practices in how we plan, execute and report studies.
  • Manage your work to meet deadlines and standards. Be accountable for your statistical deliverables' integrity. Provide discipline-specific insight and constructive challenge. Recognize your own development needs.
Essential Skills/Experience:
  • Provides statistical expertise to build studies and to evaluate and interpret experimental results in research projects and clinical trials. Refers to more senior statistical experts when necessary.
  • Leads own work to schedule and quality and applies a range of statistical methods
  • Demonstrates independence in delivering statistical assistance for standard building and interpretation of study data
  • Under the mentorship of a more experienced statistician, composes and analyzes complex studies. Provides statistical help for broader programs, including preclinical studies, regulatory submissions, commercialization efforts, or internal governance committee interactions.
  • Under mentorship of a statistician with greater expertise, analyzes internal and external information to inform building decisions and the development of decision criteria
  • Applies modelling and simulation to inform study design and assess robustness of results
  • Develops a Statistical Analysis Plan for study and/or project delivery
  • Produces analysis, supporting graphics and data tables for routine studies, such as in preclinical or clinical study reports, Global Medical Affairs studies or publications
  • Interprets, summarizes and communicates results of standard studies
  • Plays a role in improving methodology and offers practical solutions for problems
  • Applies statistical methodology to improve process and delivery activities
  • Contributes to crafting guidelines to improve quality, efficiency and effectiveness
  • Accountable for the quality of statistical work; provides discipline-specific understanding, perspective and thoughtful critique and is self-aware of own development needs
  • Able to solve complex problems within own area and participates in multidisciplinary teams
Desirable Skills/Experience:
  • Experience in late-stage oncology trials along with knowledge of disease endpoints and estimands
  • Proficiency in SAS and R, with experience in reproducible workflows and version control
  • Familiarity with regulatory guidelines and submissions, including ICH E9 and related addenda
  • Experience with Bayesian or simulation-based design approaches and decision frameworks
  • Strong communication skills to influence non-statistical partners and present at governance forums
  • Record of contributions to publications or conference presentations
When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions.That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.Why AstraZeneca:Here you will see the impact of your statistics in real time: shaping high-stakes decisions, influencing study strategies and contributing directly to medicines that change lives. We bring diverse authorities together to take on tough problems, learn fast from feedback and setbacks, and keep moving forward with courage and curiosity. You will engage with brand new methods and technology and collaborate across global programs. You will be recognized for your expertise while growing in an encouraging environment that values kindness alongside ambition.Call to Action:Step into a high-visibility role where your statistical leadership will shape late-oncology decisions and deliver meaningful outcomes for patients—take the next step in your impact today!⠀ Annual base salary for this position ranges from 109,148.80 to 143,257.80.AstraZeneca is committed to providing fair and equitable compensation opportunities to all colleagues. Our compensation policies and practices have been designed to allow colleagues to progress through the salary range over time as they progress in their role. The range provided in this posting represents an offer pay range used in a majority of situations. The base pay offered will vary depending on multiple individualized factors, including the candidate's skills and experience, job-related knowledge, and other specific business and organizational needs. In some cases, offers outside the range may also be considered to address unique circumstances.In addition, our permanent positions offer an annual Variable Pay Bonus/Short Term Incentive opportunity as well as eligibility to participate in our equity-based long-term incentive program (if applicable to role). Benefits offered for permanent roles include a competitive Flex Benefits & Retirement Savings Program, 4 weeks’ paid vacation, and annual Personal Days. Fixed Term Contract/Temporary positions (excluding students) are offered a Contract Benefits Program.We are using AI as part of the recruitment process.This advertisement relates to a current vacancy.

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